Canalization of Gene Expression and Domain Shifts in the Drosophila Blastoderm by Dynamical Attractors

@article{Manu2009CanalizationOG,
  title={Canalization of Gene Expression and Domain Shifts in the
                        Drosophila Blastoderm by Dynamical Attractors},
  author={Manu and Svetlana Surkova and Alexander V. Spirov and Vitaly V. Gursky and Hilde Janssens and Ah-Ram Kim and Ovidiu Radulescu and Carlos E. Vanario-Alonso and David H. Sharp and Maria Samsonova and John Reinitz},
  journal={PLoS Computational Biology},
  year={2009},
  volume={5},
  pages={563 - 565}
}
The variation in the expression patterns of the gap genes in the blastoderm of the fruit fly Drosophila melanogaster reduces over time as a result of cross regulation between these genes, a fact that we have demonstrated in an accompanying article in PLoS Biology (see Manu et al., doi:10.1371/journal.pbio.1000049). This biologically essential process is an example of the phenomenon known as canalization. It has been suggested that the developmental trajectory of a wild-type organism is… CONTINUE READING
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