Canalization: a molecular genetic perspective.

  title={Canalization: a molecular genetic perspective.},
  author={Adam S. Wilkins},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  volume={19 3},
  • Adam S. Wilkins
  • Published 1997 in
    BioEssays : news and reviews in molecular…
The phenomenon of canalization--the genetic capacity to buffer developmental pathways against mutational or environmental perturbations--was first characterized in the late 1930s and early 1940s. Despite enormous subsequent progress in understanding the nature of the genetic material and the molecular basis of gene expression, there have been few attempts to interpret the classical work on canalization in molecular genetic terms. Some recent findings, however, bear on one form of canalization… CONTINUE READING

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