Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions

@article{Schlesinger2012CanakinumabFA,
  title={Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions},
  author={Naomi Schlesinger and Rieke E Alten and Thomas Bardin and H. Ralph Schumacher and Mark Bloch and Alberto Gimona and Gerhard Dr. Krammer and Valda Murphy and Dominik Richard and Alexander So},
  journal={Annals of the Rheumatic Diseases},
  year={2012},
  volume={71},
  pages={1839 - 1848}
}
Objectives Gouty arthritis patients for whom non-steroidal anti-inflammatory drugs and colchicine are inappropriate have limited treatment options. Canakinumab, an anti-interleukin-1β monoclonal antibody, may be an option for such patients. The authors assessed the efficacy/safety of one dose of canakinumab 150 mg (n=230) or triamcinolone acetonide (TA) 40 mg (n=226) at baseline and upon a new flare in frequently flaring patients contraindicated for, intolerant of, or unresponsive to non… 
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