Canadian Association of Gastroenterology Clinical Practice Guidelines: the use of infliximab in Crohn's disease.

@article{Fedorak2004CanadianAO,
  title={Canadian Association of Gastroenterology Clinical Practice Guidelines: the use of infliximab in Crohn's disease.},
  author={Richard N Fedorak},
  journal={Canadian journal of gastroenterology = Journal canadien de gastroenterologie},
  year={2004},
  volume={15 6},
  pages={
          367-70
        }
}
  • R. Fedorak
  • Published 1 August 2004
  • Medicine
  • Canadian journal of gastroenterology = Journal canadien de gastroenterologie
These guidelines are presented as a follow-up to the original Canadian Association of Gastroenterology Clinical Practice Guidelines: The use of infliximab in Crohn's disease, published in the Canadian Journal of Gastroenterology (1). The original guidelines represented publications between 1998 and 2000. The current guidelines have been updated to reflect knowledge gained from two pivotal randomized clinical trails, with the use of infliximab in the maintenance of inflammatory Crohn's disease… 
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35 Citations
Highly Influential Citations
3
Background Citations
10
Methods Citations
5
Results Citations
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35 Citations

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References

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Infliximab is an established treatment for steroid‐resistant and fistulating Crohn’s disease. Although efficacy has been shown in clinical trials, financial implications often limit its use and…

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Clinical experience with infliximab for Crohn's disease: the first 100 patients in Edmonton, Alberta.

The patient group in the present study realized significant clinical benefit, with minimal adverse effects, following treatment with infliximab, and clinical response rates paralleled those previously described in placebo controlled trials and retrospective clinical practice reviews.

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Infliximab, a murine chimeric monoclonal antibody directed toward tumour necrosis factor-alpha, is a highly effective treatment of active Crohn's disease, and the only drug therapy shown to be effective for the treatment of fistulizing Crohn't disease.
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