Can xylene and quercetin directly affect basic ovarian cell functions?

@article{Tarko2018CanXA,
  title={Can xylene and quercetin directly affect basic ovarian cell functions?},
  author={Adam Tarko and Aneta {\vS}tochmaľov{\'a} and Sandra Hrabovszk{\'a} and Adriana Vachanova and Abdel Halim Harrath and Saleh Alwasel and R. Grossman and Alexander V. Sirotkin},
  journal={Research in veterinary science},
  year={2018},
  volume={119},
  pages={
          308-312
        }
}
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12 Citations
Highly Influential Citations
1
Background Citations
4
Methods Citations
1
Results Citations
2

12 Citations

Effects of benzene, quercetin, and their combination on porcine ovarian cell proliferation, apoptosis, and hormone release
TLDR
Benzene and quercetin have direct stimulatory and inhibitory effects, respectively, on basic ovarian functions, and no protective action of quercETin against the effects of benzene was found.
Rutin directly affects stimulatory action of FSH on the ovarian cell
Buckwheat, rooibos, and vitex extracts can mitigate adverse effects of xylene on ovarian cells in vitro
TLDR
Observations show that xylene has the potential to suppress ovarian cell functions, and that buckwheat, rooibos, and vitex can mitigate those effects, making them natural protectors against the adverse effects of xylene on ovarian cells.
Dietary Supplementation of Flaxseed (Linum usitatissimum L.) Alters Ovarian Functions of Xylene-Exposed Mice
TLDR
It was shown that flaxseed could mitigate and prevent the major effects of xylene on the ovary and the ability of gonadotropins to affect ovarian hormone release and prevent its response to xylene has been shown.
Abatement of the Stimulatory Effect of Copper Nanoparticles Supported on Titania on Ovarian Cell Functions by Some Plants and Phytochemicals
TLDR
It is concluded that copper nanoparticles can directly stimulate ovarian cell functions, promoting ovarian cell proliferation, apoptosis, turnover, viability, and steroid hormones release; the plants buckwheat and vitex, as well as rutin and apigenin, can promote some of these ovarian functions too; and these plant additives mitigate the CuNPs/TiO2’s activity.
Potential protective effect of puncturevine (Tribulus terrestris, L.) against xylene toxicity on bovine ovarian cell functions.
TLDR
The ability of TT to modify X action on proliferation and apoptosis indicates that TT might be a natural protector against some ovarian cell disorders associated with X action, but it can also promote its adverse effects on progesterone release.
Comparative Studies on Chemical Contents and Effect in Kidney-Yang Deficiency Rats of Salt-Processed Product and Wine-Processed Product of Cuscutae Semen
TLDR
It is indicated that both SPP and WPP can improve the reproductive function of kidney-yang deficiency rats with different mechanisms, which may be due to the differences in chemical contents between WPP and SPP as well as different processing methods.
Integrated Network Pharmacology and Clinical Study to Reveal the Effects and Mechanisms of Bushen Huoxue Huatan Decoction on Polycystic Ovary Syndrome
TLDR
BHHD has a good therapeutic effect on PCOS, and its mechanisms may be related to regulating hormone levels, improving insulin resistance, alleviating inflammation, and promoting pregnancy.
Toxicological Effects of Technical Xylene Mixtures on the Female Reproductive System: A Systematic Review
TLDR
It was found that related studies with a specific focus on the effects of technical xylene on the female reproductive system were insufficient and further studies are necessary to update the existing data, thus improving the quality and reliability of risk assessment of exposure to xylene in pregnant women.
Environmental contaminants and their influence on health and female reproduction
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References

SHOWING 1-10 OF 30 REFERENCES
Can xylene and chia (Salvia hispanica L.) seed extract directly affect basic bovine ovarian cell functions
TLDR
A direct effect of both xylene and chia seed extract are proved on bovine ovarian cell proliferation, apoptosis and secretory activity, proving that chia Seed extract could not be potentially useful for natural prevention of all negative effects of xylene on reproduction.
The Phytoestrogen Quercetin Impairs Steroidogenesis and Angiogenesis in Swine Granulosa Cells In Vitro
TLDR
Data evidence shows that quercetin does not affect granulosa cell growth while it inhibits progesterone production and modifies estradiol 17β production in a dose-related manner, and the flavonoid interferes with the angiogenic process by inhibiting VEGF production as well as by altering redox status.
INFLUENCE OF PETROCHEMICAL INDUSTRY ENVIRONMENTAL CONTAMINANTS ON ANIMAL OVARIAN CELLS
TLDR
The obtained data suggest that the negative effect of BTex on reproduction can be due to their influence on ovarian cell apoptosis, proliferation, turnover and release of peptide and steroid hormones and growth factors, and that FSH and plant molecules can regulate ovarian cell functions and prevent some effects of BTEX on these cells.
Effects of quercetin on insulin-like growth factors (IGFs) and their binding protein-3 (IGFBP-3) secretion and induction of apoptosis in human prostate cancer cells
TLDR
The decreased level of IGFs could be due to the increased levels of IGFBP-3, because of the high binding affinity towards IGFs, thereby decreasing the cell proliferation, and suggesting it may be a p53-independent effector of apoptosis in prostate cancer cells.
Inhibition of Cell Growth and VEGF Expression in Ovarian Cancer Cells by Flavonoids
TLDR
Six flavonoids, including apigenin, taxifolin, luteolin, quercetin, genistein, and kaempferol, were shown to inhibit the ovarian cancer cell growth in a dose-dependent manner and naringin showed the least inhibition effect.
Quercetin-induced inhibition and synergistic activity with cisplatin – a chemotherapeutic strategy for nasopharyngeal carcinoma cells
TLDR
The study showed that quercetin exhibited synergistic effects with cisplatin against NPC cells, and implied the possibility of reducing the cisPlatin dosage required to treat NPC, with the addition of quercETin, which could reduce the risk of cis platin-associated toxicity.
Inhibitory effect of quercetin on OVCA 433 cells and presence of type II oestrogen binding sites in primary ovarian tumours and cultured cells.
TLDR
The results suggest that Q may regulate ovarian cancer cell growth through a mechanism involving a binding interaction with type II EBS, which could also be active in vivo since primary ovarian tumours contain type IIEBS.
Protective Effect of Quercetin on Chloroquine-Induced Oxidative Stress and Hepatotoxicity in Mice
TLDR
This study strongly suggests co administration of antioxidant flavonoid like quercetin along with CQ for antimalarial therapy, particularly important when CQ is administered as long-term prophylactic treatment for malaria as chronic exposure has shown to be resulting in higher dose level of drug in the body.
The spectrum of phytoestrogens in nature: our knowledge is expanding.
TLDR
Although phytoestrogen intake as food or dietary supplements, in particular soya products and the isoflavones genistein and daidzein, has been associated with "health promoting effects", some data indicate increased disease risk.
Novel regulators of rabbit reproductive functions.
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