Can we talk about microglia without neurons? A discussion of microglial cell autonomous properties in culture

@inproceedings{Neiva2014CanWT,
  title={Can we talk about microglia without neurons? A discussion of microglial cell autonomous properties in culture},
  author={Ismael Neiva and Jo{\~a}o Oliveira Malva and Jorge Valero},
  booktitle={Front. Cell. Neurosci.},
  year={2014}
}
MICROGLIAL ORIGIN AND FUNCTION Microglial cells originate from precursor cells located in the yolk sac that migrate into the developing central nervous system (CNS) around E8.5-10 in mice. Considering their origin, microglial cells could be regarded as invaders of the CNS in charge of debris clearance, just active during brain injury, infection or degeneration. In adulthood and under certain conditions, monocytes may penetrate the blood brain barrier, reach the CNS and become non-resident brain… CONTINUE READING
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