Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review.

@article{Tubiana2009CanWR,
  title={Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review.},
  author={Maurice Tubiana},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={2009},
  volume={91 1},
  pages={4-15; discussion 1-3}
}
Second primary malignancies (SPMs) occurring after oncological treatment have become a major concern during the past decade. Their incidence has long been underestimated because most patients had a short life expectancy after treatment or their follow-up was shorter than 15 years. With major improvement of long-term survival, longer follow-up, cancer registries and end-result programs, it was found that the cumulative incidence of SPM could be as high as 20% of patients treated by radiotherapy… CONTINUE READING
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