Can we predict long-term remission after somatostatin analog withdrawal in patients with acromegaly? Results from a multicenter prospective trial

@article{Vilar2013CanWP,
  title={Can we predict long-term remission after somatostatin analog withdrawal in patients with acromegaly? Results from a multicenter prospective trial},
  author={Lucio Vilar and Maria Fleseriu and Luciana Ansaneli Naves and Jos{\'e} Luciano Albuquerque and Patr{\'i}cia Sampaio Gadelha and Manuel dos Santos Faria and Gilvan Cort{\^e}s Nascimento and Renan Magalh{\~a}es Montenegro},
  journal={Endocrine},
  year={2013},
  volume={46},
  pages={577-584}
}
Somatostatin analogs (SSAs) represent the mainstay of therapy in acromegaly. One of the potential disadvantages is the expected need to maintain therapy indefinitely in previously non-irradiated patients. The aim of this multicenter prospective open trial was to evaluate the likelihood of successful discontinuation of SSA therapy in well-controlled acromegalic patients who fulfilled very strict criteria: two or more years of treatment with the long-acting SSA octreotide LAR (OCT-LAR), a stable… CONTINUE READING
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