Can vitamin C prevent complex regional pain syndrome in patients with wrist fractures? A randomized, controlled, multicenter dose-response study.

@article{Zollinger2007CanVC,
  title={Can vitamin C prevent complex regional pain syndrome in patients with wrist fractures? A randomized, controlled, multicenter dose-response study.},
  author={Paul E. Zollinger and Wim Eduard Tuinebreijer and Roelf Simon Breederveld and Robert Walter Kreis},
  journal={The Journal of bone and joint surgery. American volume},
  year={2007},
  volume={89 7},
  pages={
          1424-31
        }
}
BACKGROUND Complex regional pain syndrome type I is treated symptomatically. A protective effect of vitamin C (ascorbic acid) has been reported previously. A dose-response study was designed to evaluate its effect in patients with wrist fractures. METHODS In a double-blind, prospective, multicenter trial, 416 patients with 427 wrist fractures were randomly allocated to treatment with placebo or treatment with 200, 500, or 1500 mg of vitamin C daily for fifty days. The effect of gender, age… CONTINUE READING

Similar Papers

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 83 CITATIONS, ESTIMATED 29% COVERAGE

Use of oral vitamin C after fractures of the distal radius.

  • The Journal of hand surgery
  • 2009
VIEW 9 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Factors associated with complex regional pain syndrome type I in patients with surgically treated distal radius fracture

  • Archives of Orthopaedic and Trauma Surgery
  • 2014
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Role of vitamin C in prevention of complex regional pain syndrome after distal radius fractures: a meta-analysis

  • European Journal of Orthopaedic Surgery & Traumatology
  • 2014
VIEW 10 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2008
2018

CITATION STATISTICS

  • 13 Highly Influenced Citations

  • Averaged 4 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES

Syndrome and proposed research diagnostic criteria . International Association for the Study of Pain

J Field, DL Protheroe, RM Atkins
  • 1999

Vitamin C as a radical scavenger in the treatment of extensive burns

H Tanaka, T Matsuda, S Shimazaki, H. Matsuda
  • Int J Intensive Care
  • 1999
VIEW 1 EXCERPT