Can the adrenergic system be implicated in the pathophysiology of bladder pain syndrome/interstitial cystitis? A clinical and experimental study.

@article{Charrua2015CanTA,
  title={Can the adrenergic system be implicated in the pathophysiology of bladder pain syndrome/interstitial cystitis? A clinical and experimental study.},
  author={Ana Charrua and Rui Alexandre Peixoto Pinto and Anna M. W. Taylor and Andr{\'e} Canelas and Alfredo Ribeiro-da-Silva and C{\'e}lia Duarte Cruz and Lori Ann Birder and Francisco I. S. Cruz},
  journal={Neurourology and urodynamics},
  year={2015},
  volume={34 5},
  pages={489-96}
}
AIMS To evaluate sympathetic system activity in bladder pain syndrome/interstitial cystitis (BPS/IC) patients and to investigate if chronic adrenergic stimulation in intact rats induces BPS/IC-like bladder modifications. METHODS Clinical study--In BPS/IC patients and aged and body mass index matched volunteers TILT test was undertaken and catecholamines were measured in plasma and 24 hr urine samples. Experimental study--Phenylephrine was injected subcutaneously (14 days) to female Wistar… CONTINUE READING

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Clinical guidelines for interstitial cystitis and hypersensitive bladder updated in 2015.

International journal of urology : official journal of the Japanese Urological Association • 2016

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