Can the Site-Frequency Spectrum Distinguish Exponential Population Growth from Multiple-Merger Coalescents?
@article{Eldon2015CanTS, title={Can the Site-Frequency Spectrum Distinguish Exponential Population Growth from Multiple-Merger Coalescents?}, author={Bjarki Eldon and Matthias C. F. Birkner and Jochen Blath and Fabian Freund}, journal={Genetics}, year={2015}, volume={199}, pages={841 - 856} }
The ability of the site-frequency spectrum (SFS) to reflect the particularities of gene genealogies exhibiting multiple mergers of ancestral lines as opposed to those obtained in the presence of population growth is our focus. An excess of singletons is a well-known characteristic of both population growth and multiple mergers. Other aspects of the SFS, in particular, the weight of the right tail, are, however, affected in specific ways by the two model classes. Using an approximate likelihood…
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