Can tenascin be redundant in cancer development?

  title={Can tenascin be redundant in cancer development?},
  author={Teruyo Sakakura and Moriaki Kusakabe},
  journal={Perspectives on developmental neurobiology},
  volume={2 1},
Histological and biochemical analyses of tenascin in various human tumors have indicated that tenascin is expressed in various cancer stroma and increased in the serum, getting strong with advancement of its malignancy. Of interest, the prognostic analysis of breast and colon cancers revealed favorable survival and no lymphogenous metastasis in patients whose cancer expressed tenascin strongly. Injection of tenascin nonproducing A431 human epidermoid cancer cells into nude mice resulted in… CONTINUE READING