Can screening for genetic markers improve peripheral artery bypass patency?

@article{Kibbe2002CanSF,
  title={Can screening for genetic markers improve peripheral artery bypass patency?},
  author={Melina R Kibbe and Andrea L. Cortese Hassett and Frances McSherry and Philip Conner and Franklin A. Bontempo and William O Williford and Willard Johnson and Michel S. Makaroun},
  journal={Journal of vascular surgery},
  year={2002},
  volume={36 6},
  pages={1198-206}
}
OBJECTIVE Three genetic mutations have been associated with an increased risk of thromboembolic events: factor V Leiden R506Q, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T (MTHFR) mutations. The aim of this study was to determine the effect of these mutations on patency of peripheral bypass procedures and preoperative and postoperative thromboembolic events. METHODS Two hundred forty-four randomly selected volunteers participating in the Veterans Affairs Cooperative… CONTINUE READING