Can prostate specific antigen derivatives and pathological parameters predict significant change in expectant management criteria for prostate cancer?

@article{Khan2003CanPS,
  title={Can prostate specific antigen derivatives and pathological parameters predict significant change in expectant management criteria for prostate cancer?},
  author={Masood Ahmed Khan and Herbert Ballentine Carter and Jonathan I. Epstein and Michael C. Miller and Patricia B Landis and Patrick W Walsh and Alan W. Partin and Robert Veltri},
  journal={The Journal of urology},
  year={2003},
  volume={170 6 Pt 1},
  pages={2274-8}
}
PURPOSE A prior report established that pretreatment criteria based on clinical and biopsy pathology parameters can predict men who harbor small volume prostate cancer who might be followed expectantly. However, some of these men will exhibit disease progression with time and will need definitive therapy. To detect those in whom disease may progress, repeat prostate biopsies are performed at yearly intervals. Therefore, we determined whether biomarkers could be used to determine those in whom… CONTINUE READING