Can probiotics modulate human disease by impacting intestinal barrier function?

@inproceedings{Bron2017CanPM,
  title={Can probiotics modulate human disease by impacting intestinal barrier function?},
  author={Peter A. Bron and Michiel Kleerebezem and Robert Jan M Brummer and Patrice D Cani and Annick Mercenier and Thomas Macdonald and C L Garcia-Rodenas and Jerry M. Wells},
  booktitle={The British journal of nutrition},
  year={2017}
}
Intestinal barrier integrity is a prerequisite for homeostasis of mucosal function, which is balanced to maximise absorptive capacity, while maintaining efficient defensive reactions against chemical and microbial challenges. Evidence is mounting that disruption of epithelial barrier integrity is one of the major aetiological factors associated with several gastrointestinal diseases, including infection by pathogens, obesity and diabetes, necrotising enterocolitis, irritable bowel syndrome and… CONTINUE READING
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