Can permeability measurements add to blood volume measurements in differentiating tumefactive demyelinating lesions from high grade gliomas using perfusion CT?

@article{Jain2009CanPM,
  title={Can permeability measurements add to blood volume measurements in differentiating tumefactive demyelinating lesions from high grade gliomas using perfusion CT?},
  author={Rajan Jain and Shehanaz Ellika and Norman L Lehman and Lisa Scarpace and Lonni R. Schultz and Jack P. Rock and Mark L. Rosenblum and T. G. Mikkelsen},
  journal={Journal of Neuro-Oncology},
  year={2009},
  volume={97},
  pages={383-388}
}
Tumefactive demyelinating lesions (TDLs) can mimic a neoplasm on conventional imaging and may necessitate biopsy for diagnosis. The purpose of this study was to differentiate TDLs from high grade gliomas based on physiologic (permeability) and hemodynamic (blood volume) parameters using perfusion CT. Five patients who presented with tumefactive enhancing lesions on initial MRI that mimicked a neoplasm underwent perfusion CT. We compared the perfusion CT parameters of these patients with those… CONTINUE READING

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