Can molgramostim enhance the antitumor effects of cytotoxic drugs in patients with advanced sarcomas?

@article{Edmonson1997CanME,
  title={Can molgramostim enhance the antitumor effects of cytotoxic drugs in patients with advanced sarcomas?},
  author={John H. Edmonson and Harry J. Long and Larry K. Kvols and Bhupinder Singh Mann and Joseph Patrick Grill},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={1997},
  volume={8 7},
  pages={637-41}
}
BACKGROUND A phase I study was designed for the amalgamation of two previously studied antisarcoma regimens (ifosfamide+doxorubicin and mitomycin+doxorubicin+cisplatin) supported by molgramostim. Thus, we hoped to develop a better regimen for the treatment of advanced sarcomas. PATIENTS AND METHODS Fifteen adult advanced sarcoma patients and six other patients were registered and sequentially assigned to receive three progressively more myelosuppressive levels of chemotherapy: level I… CONTINUE READING
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