Can medial temporal lobe regions distinguish true from false? An event-related functional MRI study of veridical and illusory recognition memory
@article{Cabeza2001CanMT, title={Can medial temporal lobe regions distinguish true from false? An event-related functional MRI study of veridical and illusory recognition memory}, author={Roberto Cabeza and Stephen M. Rao and Anthony D. Wagner and Andrew R. Mayer and Daniel L. Schacter}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2001}, volume={98}, pages={4805 - 4810} }
To investigate the types of memory traces recovered by the medial temporal lobe (MTL), neural activity during veridical and illusory recognition was measured with the use of functional MRI (fMRI). Twelve healthy young adults watched a videotape segment in which two speakers alternatively presented lists of associated words, and then the subjects performed a recognition test including words presented in the study lists (True items), new words closely related to studied words (False items), and…
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References
SHOWING 1-10 OF 103 REFERENCES
Functional differentiation of medial temporal and frontal regions involved in processing novel and familiar words: an fMRI study.
- Biology, PsychologyBrain : a journal of neurology
- 1999
Evidence is provided for an anterior-posterior functional differentiation within the MTL in processing novel and familiar verbal information and the finding of left MTL lateralization is consistent with lesion-based material-specific models of memory.
Late Onset of Anterior Prefrontal Activity during True and False Recognition: An Event-Related fMRI Study
- Psychology, BiologyNeuroImage
- 1997
Event-related analyses of time course data show a relatively late onset and sustained duration for anterior prefrontal signal changes compared to signal changes in other activated regions, consistent with the idea that anterior prefrontal regions participate in postretrieval monitoring processes.
FMRI activity in the medial temporal lobe during recognition memory as a function of study‐test interval
- Biology, PsychologyHippocampus
- 2000
The phenomenon of temporally graded retrograde amnesia (loss of information acquired before the onset of amnesia) suggests that the hippocampus, and possibly other medial temporal lobe (MTL)…
Neural Correlates of Episodic Retrieval Success
- Psychology, BiologyNeuroImage
- 2000
It is suggested that left frontal and parietal regions modulate activity based on the successful retrieval of information from episodic memory.
Recollection and Familiarity in Recognition Memory: An Event-Related Functional Magnetic Resonance Imaging Study
- Psychology, BiologyThe Journal of Neuroscience
- 1999
It is suggested that the responses of different brain regions do dissociate according to the phenomenology associated with memory retrieval, and both R and K judgments for studied words and N judgments for unstudied words were associated with enhanced responses.
Retrieval Success is Accompanied by Enhanced Activation in Anterior Prefrontal Cortex During Recognition Memory: An Event-Related fMRI Study
- Psychology, BiologyJournal of Cognitive Neuroscience
- 2000
This method of instantiating retrieval success under conditions in which the target word had not been studied offers converging evidence for the claim that anterior-prefrontal cortex (among other regions) demonstrates enhanced activation during retrieval success.
Novelty and familiarity activations in PET studies of memory encoding and retrieval.
- PsychologyCerebral cortex
- 1996
A 'novelty/encoding hypothesis': novelty assessment represents an early stage of long-term memory encoding and elaborate, meaning-based encoding processes operate on the incoming information to the extent of its novelty, and therefore the probability ofLong-term storage of information varies directly with the novelty of the information.
Functional–Anatomic Study of Episodic Retrieval II. Selective Averaging of Event-Related fMRI Trials to Test the Retrieval Success Hypothesis
- Psychology, BiologyNeuroImage
- 1998
Findings in right anterior prefrontal cortex go against the retrieval success hypothesis as formally proposed and provide an important constraint for interpretation of this region's role in episodic retrieval.
Differential activation of the prefrontal cortex in successful and unsuccessful memory retrieval.
- PsychologyBrain : a journal of neurology
- 1996
It is concluded that the prefrontal cortex, especially in the right hemisphere, is more active when a retrieval attempt succeeds than when it fails, consistent with the idea that the cortex supports processes that operate selectively on the products of memory retrieval.
Neuroanatomical correlates of retrieval in episodic memory: auditory sentence recognition.
- Psychology, BiologyProceedings of the National Academy of Sciences of the United States of America
- 1994
The prevalence of sulcal blood-flow changes may reflect extensive cortical gyrification; it may also indicate that memory-related processes rely on the densely packed neuropil of sulCal regions.