Can lower aldehyde dehydrogenase activity in saliva be a risk factor for oral cavity cancer?

@article{Giebutowicz2013CanLA,
  title={Can lower aldehyde dehydrogenase activity in saliva be a risk factor for oral cavity cancer?},
  author={Joanna Giebułtowicz and Piotr Wroczyński and Danuta Samolczyk-Wanyura},
  journal={Oral diseases},
  year={2013},
  volume={19 8},
  pages={763-6}
}
OBJECTIVES Salivary ALDH3A1 protects the oral cavity from aromatic and medium-chain aliphatic aldehydes originating from food and air pollution and generated during oxidative stress. Due to their reactivity, aldehydes may exhibit an irritating effect as well as cytotoxic, genotoxic, mutagenic and even carcinogenic effects. The aim of this study was to verify whether lower ALDH3A1 activity is a risk factor for oral cavity cancer. SUBJECTS AND METHODS Fasting saliva samples were collected one… CONTINUE READING
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