Can heparin immobilized surfaces maintain nonthrombogenic activity during in vivo long-term implantation?

@article{Nojiri1996CanHI,
  title={Can heparin immobilized surfaces maintain nonthrombogenic activity during in vivo long-term implantation?},
  author={Chisato Nojiri and Tetsuo Kido and Takashi Sugiyama and Katsuhiro Horiuchi and Toshihiko Kijima and Kyohei Hagiwara and E Kuribayashi and Atsuhiko Nogawa and Kazutaka Ogiwara and Toshinosuke Akutsu},
  journal={ASAIO journal},
  year={1996},
  volume={42 5},
  pages={M468-75}
}
The authors previously demonstrated that heparin immobilized surfaces showed excellent nonthrombogenic properties for extracorporeal membrane oxygenation experiments as long as 168 hr. The characteristics of the heparin immobilized surfaces include high heparin bioactivity and prevention of platelet adhesion and complement activation. However, it is not… CONTINUE READING