Can expression of apoptosis genes, bcl-2 and bax, predict survival and responsiveness to chemotherapy in node-negative breast cancer patients?

@article{Kymionis2001CanEO,
  title={Can expression of apoptosis genes, bcl-2 and bax, predict survival and responsiveness to chemotherapy in node-negative breast cancer patients?},
  author={George D. Kymionis and Constantine Dimitrakakis and Manousos M. Konstadoulakis and Iordanis Arzimanoglou and Emmanuel A. Leandros and George E. Chalkiadakis and Antonios Keramopoulos and Stylianos Michalas},
  journal={The Journal of surgical research},
  year={2001},
  volume={99 2},
  pages={161-8}
}
BACKGROUND Although the status of the axillary lymph nodes is widely accepted to be associated with prognosis in breast cancer patients, there is a need for biomarkers to be analyzed as indicators of responsiveness to treatment. The objective of this study was to test the hypothesis that the expression of apoptosis genes, bcl-2 and bax, predicts survival and responsiveness to chemotherapy in node-negative breast cancer patients. METHODS One hundred thirty premenopausal women with primary… CONTINUE READING
22 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Similar Papers

Loading similar papers…