Can digoxin dose requirements be predicted?

  title={Can digoxin dose requirements be predicted?},
  author={Sylvia M. Dobbs and G E Mawer and Mary Rodgers and Barry G. Woodcock and Samuel B. Lucas},
  journal={British journal of clinical pharmacology},
  volume={3 2},
A search for patient variables relevant to digoxin dose requirements was made in fourty-three patients with a wide range of renal and hepatic function. The daily dose of digoxin to achieve a mean serum concentration of 1.5 ng/ml, the standardized dose, was calculated for each patient. The standardized dose correlated significantly with the following variables, in descending order of correlation coefficient; creatinine clearance, serum creatinine concentration, body weight and serum albumin… CONTINUE READING

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