Can chemotherapy concomitantly delivered with radiotherapy improve survival of patients with resectable rectal cancer? A meta-analysis of literature data.

@article{Fiorica2010CanCC,
  title={Can chemotherapy concomitantly delivered with radiotherapy improve survival of patients with resectable rectal cancer? A meta-analysis of literature data.},
  author={Francesco Fiorica and Francesco Cartei and Anna Licata and M. R. Enea and Stefano Ursino and Caterina Colosimo and Calogero Camm{\`a}},
  journal={Cancer treatment reviews},
  year={2010},
  volume={36 7},
  pages={539-49}
}
BACKGROUND There is clear evidence from two systematic reviews that radiotherapy (RT) reduces the risk of local recurrence in patients with resectable rectal cancer, though the data on survival are still equivocal. OBJECTIVE To assess the effects of chemotherapy combined concomitantly with radiotherapy (CRT) on the increase of overall survival, and on the prevention of local recurrence and distant metastases. DATA SOURCES Computerized bibliographic searches of MEDLINE and CANCERLIT (1970… CONTINUE READING