Can chemoprophylaxis against opportunistic infections be discontinued after an increase in CD4 cells induced by highly active antiretroviral therapy?

@article{Kirk1999CanCA,
  title={Can chemoprophylaxis against opportunistic infections be discontinued after an increase in CD4 cells induced by highly active antiretroviral therapy?},
  author={Ole Kirk and Jens D. Lundgren and Court Pedersen and Henrik Krarup Nielsen and Jan Gerstoft},
  journal={AIDS},
  year={1999},
  volume={13 13},
  pages={1647-51}
}
BACKGROUND In the 'USPHS/IDSA Guidelines for Prevention of Opportunistic Infections in Persons Infected with Human Immunodeficiency Virus', the indications for chemoprophylaxis are based on nadir CD4 cell count. Many patients have, however, experienced an increase in CD4 cell count after the introduction of highly active antiretroviral therapy (HAART). OBJECTIVES To assess incidences of opportunistic infections after discontinuation of chemoprophylaxis in HIV-infected patients, who have… CONTINUE READING