Can calcium chemoprevention of adenoma recurrence substitute or serve as an adjunct for colonoscopic surveillance?

@article{Shaukat2009CanCC,
  title={Can calcium chemoprevention of adenoma recurrence substitute or serve as an adjunct for colonoscopic surveillance?},
  author={Aasma Shaukat and Murtaza Parekh and Joseph Lipscomb and Uri Ladabaum},
  journal={International journal of technology assessment in health care},
  year={2009},
  volume={25 2},
  pages={222-31}
}
OBJECTIVES The aim of this study was to examine the potential cost-effectiveness of calcium chemoprevention post-polypectomy as a substitute or adjunct for surveillance. METHODS We constructed a Markov model of post-polypectomy adenoma recurrence and colorectal cancer (CRC) development, calibrated to data from prospective chemoprevention trials of fiber, calcium, antioxidants, and aspirin. We modeled four scenarios for 50-year-old patients immediately after polypectomy: (i) natural history… CONTINUE READING