Can anti-IgE be used to treat allergy?

@article{Davis2004CanAB,
  title={Can anti-IgE be used to treat allergy?},
  author={F. Davis and L. A. Gossett and K. Pinkston and R. Liou and L. Sun and Y. Kim and N. Chang and T. Chang and K. Wagner and J. Bews and V. Brinkmann and H. Towbin and N. Subramanian and C. Heusser},
  journal={Springer Seminars in Immunopathology},
  year={2004},
  volume={15},
  pages={51-73}
}
Summary and conclusionA summary of the properties of CGP 51901 is shown in Table 3. On the basis of its binding to IgE and IgE-secreting cells and its activity in vitro and in vivo, CGP 51901 is expected to be able to decrease serum IgE by direct clearance of IgE and by reduction of the numbers and productivity of IgE-secreting cells. The end result of reduction of IgE in the circulation and on mast cells is expected to be the attenuation of IgE-mediated reactions and the improvement in allergy… Expand
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