Can We Use Diet to Effectively Treat Esophageal Disease? A Review of the Current Literature

  title={Can We Use Diet to Effectively Treat Esophageal Disease? A Review of the Current Literature},
  author={C. Newberry and Kristle L. Lynch},
  journal={Current Gastroenterology Reports},
Purpose of ReviewEsophageal diseases represent a wide variety of conditions affecting esophageal anatomy, physiology, and motility. Therapy focuses on pharmacotherapy and endoscopic or surgical management. Dietary therapy can be considered in management algorithms for specific esophageal diseases. This review focuses on outlining the literature related to dietary therapy in gastroesophageal reflux disease, eosinophilic esophagitis, Barrett’s esophagus, and esophageal adenocarcinoma.Recent… Expand

Paper Mentions

Interventional Clinical Trial
Prospective, pragmatic standard of care clinical trial comparing dietary therapies of standard dairy elimination diet alone (DED) to dairy elimination plus food additive… Expand
ConditionsEosinophilic Esophagitis
Treatment Results for Gastroesophageal Reflux Disease
Gastroesophageal reflux disease is a common condition with symptoms that can significantly affect quality of life and lead to potential long-term consequences. Multiple mechanisms can predispose toExpand
Are Diet and Micronutrients Effective in Treating Gastroesophageal Reflux Disease Especially in Women?
The authors evaluated the effect of micronutrient intake on erosive esophagitis and non-erosive reflux disease (NERD) including 11 690 participants who underwent endoscopy and completed questionnaires for reflux symptoms and dietary intake and found high dietary intake of calcium reduced the risk of NERD in men. Expand
An Alternative Approach to the Gastroesophageal Reflux Disease: Manual Techniques and Nutrition
A simple treatment plan for manual therapists is presented based on current evidence-based literature; it is designed to reduce symptoms of GERD through somatovisceral approach and the nutrition. Expand
Lifestyle and Dietary Modifications
This chapter will explore lifestyle and dietary modifications and their rationale for patients with laryngopharyngeal reflux and will discuss the evidence where available. Expand
Reflux Cure - Transitioning to a Plant-Based Diet from the Standard American Diet (SAD)
This chapter reviews the evidence-based benefits of a comprehensive plant-based diet that can be a treatment strategy for laryngopharyngeal reflux (LPR) and gastroesophageal reflux disease (GERD).Expand
Nutrition and gastrointestinal disorders
Effects of the diet and nutrition on disease processes as well as from therapeutic aspects for conditions including gastroesophageal reflux, eosinophilic esophagitis, celiac disease, inflammatory bowel disease and for functional gastrointestinal disorders are also discussed. Expand
Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux
RedS, RESDI and GRES are proposed as objective scores for assessing the refluxogenic potential of F&B composing a dish or the overall diet of LPR patients, respectively. Expand
Effects of Six-Food Elimination Diet on Esophageal Symptoms and Histopathology in Adult Patients with Eosinophilic Esophagitis
The author examines the links between eosinophilic esophagitis, which is linked to GERD, and EoE, a leading cause of esophageal cancer in children and adults, and investigates the mechanisms behind this link. Expand


Efficacy of dietary interventions for inducing histologic remission in patients with eosinophilic esophagitis: a systematic review and meta-analysis.
Dietary interventions are effective in producing histologic remission in patients with EoE, and Elemental diets and SFEDs were the most effective, achieving <15 eosinophils/high-power field in 90.8% and 72.1% of patients, respectively. Expand
Barrett's esophagus, esophageal and esophagogastric junction adenocarcinomas: the role of diet.
A review of the literature to investigate the association between specific dietary components and the risk of Barrett’s esophagus, EAC and EGJAC found an inverse association with increased intake of fruit, vegetables and antioxidants has been reported but this association was not consistent across all studies reviewed. Expand
Are Lifestyle Measures Effective in Patients With Gastroesophageal Reflux Disease?: An Evidence-Based Approach
Although there was physiologic evidence that exposure to tobacco, alcohol, chocolate, and high-fat meals decreases lower esophageal sphincter pressure, there was no published evidence of the efficacy of dietary measures. Expand
Meta-Analysis-Based Guidance for Dietary Management in Eosinophilic Esophagitis
  • A. Lucendo
  • Medicine
  • Current Gastroenterology Reports
  • 2015
This review provides evidence-based insights into the dietary management of EoE and empiric elimination of common food allergens is now recognized as the best alternative for dietary treatment, with moderate-to-high efficiency and reproducible results. Expand
Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula.
Chronic gastrointestinal symptoms and histological changes of the esophagus unresponsive to standard treatments for gastroesophageal reflux were improved by the use of elemental formulas. Expand
Eosinophilic Esophagitis From an Allergy Perspective: How to Optimally Pursue Allergy Testing & Dietary Modification in the Adult Population
This article will review the existing data on these dietary therapies and will propose an approach to dietary management in adult EoE. Expand
Dietary elimination therapy is an effective option for adults with eosinophilic esophagitis.
Dietary elimination is a successful treatment modality for adults with EoE and further research should emphasize which factors can predict effective dietary therapy. Expand
Lifestyle Intervention in Gastroesophageal Reflux Disease.
Weight loss and tobacco smoking cessation should be recommended to GERD patients who are obese and smoke, respectively and avoiding late evening meals and head-of-the-bed elevation is effective in nocturnal GERD. Expand
Different effects of dietary factors on reflux esophagitis and non-erosive reflux disease in 11,690 Korean subjects
While many food groups affected NERD, reflux esophagitis was associated with BMI and total energy intake rather than dietary component. Expand
Treatment of eosinophilic esophagitis with specific food elimination diet directed by a combination of skin prick and patch tests.
In more than 75% of patients with EE, both symptoms and esophageal inflammation can be significantly improved with dietary elimination of foods, and skin prick and atopy patch testing can help identify foods in most patients. Expand