Can Pha Act

Abstract

ownloade pose: This dose-escalation study evaluated the safety, tolerability, and pharmacokinetics (PK) of al Src inhibitor saracatinib (AZD0530) in patients with advanced solid malignancies. Tumor biopsy es were taken to investigate the effect of saracatinib on Src activity in tumors. erimental Design: Part A of the study followed a multiple-ascending dose… (More)

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