Can Intra-Y Gene Conversion Oppose the Degeneration of the Human Y Chromosome? A Simulation Study


The human Y is a genetically degenerate chromosome, which has lost about 97% of the genes originally present. Most of the remaining human Y genes are in large duplicated segments (ampliconic regions) undergoing intense Y-Y gene conversion. It has been suggested that Y-Y gene conversion may help these genes getting rid of deleterious mutations that would… (More)
DOI: 10.1093/gbe/evq026


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