Can Interferon-Gamma or Interferon-Gamma-Induced-Protein-10 Differentiate Tuberculosis Infection and Disease in Children of High Endemic Areas?

@inproceedings{Yassin2011CanIO,
  title={Can Interferon-Gamma or Interferon-Gamma-Induced-Protein-10 Differentiate Tuberculosis Infection and Disease in Children of High Endemic Areas?},
  author={Mohammed Ahmed Yassin and Roberta Petrucci and Kefyalew Taye Garie and Gregory Harper and Isabel Arbide and Melkamsew Aschalew and Yared Merid and Zelalem Kebede and Amin Ahmed Bawazir and Nabil Mohamed Abuamer and Luis E Cuevas},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Diagnosis of childhood tuberculosis (TB) is difficult in high TB burden settings. Interferon-gamma-induced protein 10 (IP10) has been suggested as a marker of TB infection and disease, but its ability to differentiate the two conditions remains uncertain. OBJECTIVES To describe Interferon-gamma (INFγ) and IP10 expression in children with TB infection and disease and controls to assess their potential to differentiate latent and active TB. METHODS This was a cross sectional study… CONTINUE READING

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