Can Endogenous, Noise-Triggered Early after-Depolarizations Initiate reentry in a Modified Luo-rudy Ventricular Virtual Tissue?

Abstract

EADs were produced by lowered gK,s in Luo–Rudy cell models, and could be triggered by the addition of a small noise current. Endogenous EADs, produced in a fully deterministic, or a noise driven, one-dimensional virtual tissue could initiate ectopic (unidirectional or bidirectional) propagation, and retrograde, unidirectional propagation that is the analogue of reentry in a twodimensional tissue. Such potentially reentrant activity occurred with a low probability, for a very narrow parameter range.

DOI: 10.1142/S0218127403008934

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Cite this paper

@article{Clayton2003CanEN, title={Can Endogenous, Noise-Triggered Early after-Depolarizations Initiate reentry in a Modified Luo-rudy Ventricular Virtual Tissue?}, author={Richard H. Clayton and Arun V. Holden and W. C. Tong}, journal={I. J. Bifurcation and Chaos}, year={2003}, volume={13}, pages={3835-3843} }