Can Endogenous, Noise-Triggered Early after-Depolarizations Initiate reentry in a Modified Luo-rudy Ventricular Virtual Tissue?

@article{Clayton2003CanEN,
  title={Can Endogenous, Noise-Triggered Early after-Depolarizations Initiate reentry in a Modified Luo-rudy Ventricular Virtual Tissue?},
  author={Richard H. Clayton and Arun V. Holden and W. C. Tong},
  journal={I. J. Bifurcation and Chaos},
  year={2003},
  volume={13},
  pages={3835-3843}
}
EADs were produced by lowered gK,s in Luo–Rudy cell models, and could be triggered by the addition of a small noise current. Endogenous EADs, produced in a fully deterministic, or a noise driven, one-dimensional virtual tissue could initiate ectopic (unidirectional or bidirectional) propagation, and retrograde, unidirectional propagation that is the analogue of reentry in a twodimensional tissue. Such potentially reentrant activity occurred with a low probability, for a very narrow parameter… CONTINUE READING