Can ECT-induced cognitive effects be altered pharmacologically?


1. A systematic review of the literature revealed twelve clinical trials that evaluated nine different drugs, and used three different conceptual models to prevent, restore or treat ECT-induced cognitive deficits. 2. This review indicated inconclusive results regarding clinical utility of any of the drugs. 3. Major factors discussed include the complexities involved in the evaluation of ECT-induced cognitive deficits, and the techniques of evaluating changes in cognitive functions. 4. Our conclusion is that future research should emphasize understanding the neural mechanisms related to ECT-induced cognitive deficits. We suggest several areas for future exploration.

Cite this paper

@article{Khan1993CanEC, title={Can ECT-induced cognitive effects be altered pharmacologically?}, author={Ashraf Khan and Mary H. Mirolo and Hugh A Mirolo and Sharyn Slavin Miller}, journal={Progress in neuro-psychopharmacology & biological psychiatry}, year={1993}, volume={17 6}, pages={861-73} }