Calreticulin in rainbow trout: a limited response to endoplasmic reticulum (ER) stress.

@article{Kales2007CalreticulinIR,
  title={Calreticulin in rainbow trout: a limited response to endoplasmic reticulum (ER) stress.},
  author={Stephen Charles Kales and Niels Christian Bols and B Dixon},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology},
  year={2007},
  volume={147 4},
  pages={
          607-15
        }
}
Calreticulin (CRT) is a resident protein of the endoplasmic reticulum where it serves as a calcium modulator and chaperone to newly synthesized glycoproteins. In mammals, CRT is a structurally conserved 46 kDa protein that demonstrates anomalous migration at 60 kDa on SDS polyacrylamide gels and can be up-regulated by A23187 and thapsigargin due to the endoplasmic reticulum stress elements (ERSE) in the promoter region of its gene. CRT has numerous proposed functions and has been localized to… CONTINUE READING
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