Calprotectin induces cell death in human prostate cancer cell (LNCaP) through survivin protein alteration.


Calprotectin (CP), an abundant heterodimeric cytosolic protein of neutrophils, conveys a variety of functions such as tumor cell growth arrest and antimicrobial activity. We investigated CP activity and its possible apoptosis-inducing mechanism of action against an antiandrogen therapy-resistance prostate cancer cell line LNCaP. Cell viability and Annexin V… (More)
DOI: 10.1002/cbin.10328