Calprotectin as a Biomarker for Rheumatoid Arthritis: A Systematic Review

@article{Abildtrup2015CalprotectinAA,
  title={Calprotectin as a Biomarker for Rheumatoid Arthritis: A Systematic Review},
  author={Mads Abildtrup and G. Kingsley and D. Scott},
  journal={The Journal of Rheumatology},
  year={2015},
  volume={42},
  pages={760 - 770}
}
  • Mads Abildtrup, G. Kingsley, D. Scott
  • Published 2015
  • Medicine
  • The Journal of Rheumatology
  • Objective. Calprotectin (myeloid-related protein 8/14), a heterodimeric complex of calcium-binding proteins, is expressed in granulocytes and monocytes. Calprotectin levels are high in synovial tissue, particularly in activated cells adjacent to the cartilage-pannus junction. This systematic review evaluates the use of calprotectin as an indicator of disease activity, therapeutic response, and prognosis in rheumatoid arthritis (RA). Methods. Medline, Scopus, and the Cochrane Library (1970–2013… CONTINUE READING
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