Calpain localization changes in coordination with actin-related cytoskeletal changes during early embryonic development of Drosophila.

@article{Emori1994CalpainLC,
  title={Calpain localization changes in coordination with actin-related cytoskeletal changes during early embryonic development of Drosophila.},
  author={Y. Emori and Kaoru Saigo},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 40},
  pages={25137-42}
}
Calpain, a calcium-dependent intracellular protease, was identified in Drosophila melanogaster. Drosophila calpain has an amino acid sequence highly homologous to those of mammalian calpains and exhibits a distinct domain structure consisting of cysteine protease and calcium-binding domains. Specific antibodies raised against a recombinant calpain fragment were used to identify the localization of calpain in developing Drosophila embryos. Calpain was first detected near the anterior pole and in… CONTINUE READING