Calpain-like and lactate dehydrogenase activities in the cerebrospinal fluid of patients with amyotrophic lateral sclerosis

@article{Brylev2007CalpainlikeAL,
  title={Calpain-like and lactate dehydrogenase activities in the cerebrospinal fluid of patients with amyotrophic lateral sclerosis},
  author={L. V. Brylev and Alexander A. Yakovlev and Mikhail V. Onufriev and Mariya N Zakharova and Igor A Zavalishin and Natalia V. Gulyaeva},
  journal={Neurochemical Journal},
  year={2007},
  volume={1},
  pages={326-333}
}
Amyotrophic lateral sclerosis (ALS) is neurodegenerative disease accompanied by the death of motor neurons. To clarify the role of calpain in the ALS-induced death of neurons, we measured the calpainlike and lactate dehydrogenase (LDH) activities in the cerebrospinal fluid (CSF) of ALS patients and patients of a control group. The LDH activity measured in… CONTINUE READING