Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment


Prostate cancer will develop chemoresistance following a period of chemotherapy. This is due, in part, to the acquisition of antiapoptotic properties by the cancer cells and, therefore, development of novel strategies for treatment is of critical need. Here, we attempt to clarify the role of the antiapoptotic molecule galectin-3 in prostate cancer cells… (More)
DOI: 10.1038/cddis.2010.79


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