Calorie restriction limits the generation but not the progression of mitochondrial abnormalities in aging skeletal muscle

@article{Bua2004CalorieRL,
  title={Calorie restriction limits the generation but not the progression of mitochondrial abnormalities in aging skeletal muscle},
  author={Entela Bua and S. McKiernan and J. Aiken},
  journal={The FASEB Journal},
  year={2004},
  volume={18}
}
The effect of early‐onset calorie restriction and aging on the accumulation of electron transport system (ETS) abnormalities was studied in rat skeletal muscle. Rectus femoris and vastus lateralis muscle fibers were analyzed for cytochrome c oxidase (COX) and succinate dehydrogenase (SDH) enzyme activities. Fibers displaying COX negative and SDH hyper reactive (COX–/SDH++) phenotype were followed through 1000–2000 micrometers to determine the frequency and length of these abnormalities as well… Expand
View on Wiley
ncbi.nlm.nih.gov
51 Citations
Highly Influential Citations
2
Background Citations
22
Methods Citations
1
Results Citations
4

51 Citations

Citation Type

Citation Type

Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle
  • 70
Adult-onset calorie restriction delays the accumulation of mitochondrial enzyme abnormalities in aging rat kidney tubular epithelial cells.
  • 50
  • PDF
Synergistic effects of caloric restriction with maintained protein intake on skeletal muscle performance in 21‐month‐old rats: a mitochondria‐mediated pathway
  • 61
Absence of uncoupling protein-3 leads to greater activation of an adenine nucleotide translocase-mediated proton conductance in skeletal muscle mitochondria from calorie restricted mice.
  • 24
Sarcopenia of aging: Underlying cellular mechanisms and protection by calorie restriction
  • 140
Calorie restriction in mice overexpressing UCP3: Evidence that prior mitochondrial uncoupling alters response
  • 10
Apoptosis and necrosis mediate skeletal muscle fiber loss in age‐induced mitochondrial enzymatic abnormalities
  • 44
Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding
  • 45
  • Highly Influenced
Tumor necrosis factor α signaling in skeletal muscle: effects of age and caloric restriction
  • 77
Aging and Calorie Restriction Oppositely Affect Mitochondrial Biogenesis through TFAM Binding at Both Origins of Mitochondrial DNA Replication in Rat Liver
  • 53
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 37 REFERENCES
Influences of Caloric Restriction on Age‐associated Skeletal Muscle Fiber Characteristics and Mitochondrial Changes in Rats and Mice a
  • 57
Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle
  • 157
Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia.
  • 197
  • PDF
Early‐onset calorie restriction conserves fiber number in aging rat skeletal muscle
  • 79
Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle.
  • 166
  • PDF
Molecular mechanisms linking calorie restriction and longevity.
  • B. Merry
  • Biology, Medicine
  • The international journal of biochemistry & cell biology
  • 2002
  • 287
Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys.
  • 71
Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia
  • 343
Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria.
  • 271
Cellular and molecular basis of age-related sarcopenia.
  • S. Welle
  • Biology, Medicine
  • Canadian journal of applied physiology = Revue canadienne de physiologie appliquee
  • 2002
  • 135
...
1
2
3
4
...