Caloric restriction.

  title={Caloric restriction.},
  author={John R Speakman and Sharon E. Mitchell},
  journal={Molecular aspects of medicine},
  volume={32 3},
Restricting the intake of calories has been practiced as a method for increasing both the length and quality of life for over 500 years. Experimental work confirming the success of this approach in animals has accumulated over the last 100 years. Lifelong caloric restriction (CR) may extend life by up to 50% in rodents, with progressively less impact the later in life it is started. This effect is matched by profound impacts on age related diseases including reduced risk of cancer… CONTINUE READING
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