Caloric restriction retards the age-related decline in mitochondrial function of brown adipose tissue.

@article{Valle2008CaloricRR,
  title={Caloric restriction retards the age-related decline in mitochondrial function of brown adipose tissue.},
  author={A. Ortega Valle and Roc{\'i}o Guevara and Francisco Jos{\'e} Garc{\'i}a-Palmer and Pilar Roca and Jordi Oliver},
  journal={Rejuvenation research},
  year={2008},
  volume={11 3},
  pages={597-604}
}
Caloric restriction (CR) has been shown to prevent the age-associated loss of mitochondrial function and biogenesis in several tissues such as liver, heart, and skeletal muscle. However, little is known about the effects of CR on a tissue in which the mitochondria have no adenosine triphosphate (ATP)-producing purpose but show a high degree of uncoupling, namely brown adipose tissue (BAT). Hence, the aim of the present study was to analyze the effect of long-term CR on BAT mitochondrial… CONTINUE READING

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