Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle

@article{Aspnes1997CaloricRR,
  title={Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle},
  author={Lauren E. Aspnes and Connie M Lee and R. H. Weindruch and Susan S. Chung and Ellen B. Roecker and Judd M. Aiken},
  journal={The FASEB Journal},
  year={1997},
  volume={11},
  pages={573 - 581}
}
The influence of caloric restriction (CR) initiated at 17 months of age was investigated on selected age‐associated measures in skeletal muscle. Tissue from young (3–4 months) ad libitum‐fed, old (30–32 months) restricted (35% and 50% CR, designated CR35 and CR50, respectively), and old ad libitum‐fed rats (29 months) was studied. CR preserved fiber number and fiber type composition in the vastus lateralis muscle of the CR50 rats. In the old rats from all groups, individual fibers were found… 

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Calorie restriction limits the generation but not the progression of mitochondrial abnormalities in aging skeletal muscle

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Effectiveness of caloric restriction in preventing age-related changes in rat skeletal muscle.

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Long‐term caloric restriction abrogates the age‐related decline in skeletal muscle aerobic function

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Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle

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Skeletal muscle aging in F344BN F1-hybrid rats: I. Mitochondrial dysfunction contributes to the age-associated reduction in VO2max.

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