Caloric restriction reduces edema and prolongs survival in a mouse glioma model

@article{Jiang2013CaloricRR,
  title={Caloric restriction reduces edema and prolongs survival in a mouse glioma model},
  author={Yong-Sheng Jiang and Fu-rong Wang},
  journal={Journal of Neuro-Oncology},
  year={2013},
  volume={114},
  pages={25-32}
}
Regardless of their cell type of origin, all aggressive brain tumors, such as malignant gliomas and metastatic tumors produce brain edema, which is an important cause of patient morbidity and mortality. Caloric restriction (CR) has long been recognized as a natural therapy that improves health, promotes longevity, and significantly reduces both the incidence and growth of many tumor types. The aim of present work was to investigate the effect of CR on edema and survival in the mice implanted… CONTINUE READING