Caloric restriction improves diabetes-induced cognitive deficits by attenuating neurogranin-associated calcium signaling in high-fat diet-fed mice.

Abstract

Diabetes-induced cognitive decline has been recognized in human patients of type 2 diabetes mellitus and mouse model of obesity, but the underlying mechanisms or therapeutic targets are not clearly identified. We investigated the effect of caloric restriction on diabetes-induced memory deficits and searched a molecular mechanism of caloric restriction… (More)
DOI: 10.1177/0271678X15606724

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Cite this paper

@article{Kim2016CaloricRI, title={Caloric restriction improves diabetes-induced cognitive deficits by attenuating neurogranin-associated calcium signaling in high-fat diet-fed mice.}, author={Hwajin Kim and Heeyoung Kang and Rok Won Heo and Byeong Tak Jeon and Chin-ok Yi and Hyun Joo Shin and Jeonghyun Kim and Seon-Yong Jeong and Woori Kwak and Won-Ho Kim and Sang Soo Kang and Gu Seob Roh}, journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism}, year={2016}, volume={36 6}, pages={1098-110} }