Caloric restriction attenuates the age-associated increase of adipose-derived stem cells but further reduces their proliferative capacity

@article{Schmuck2010CaloricRA,
  title={Caloric restriction attenuates the age-associated increase of adipose-derived stem cells but further reduces their proliferative capacity},
  author={Eric G. Schmuck and Jacob D. Mulligan and Kurt W. Saupe},
  journal={AGE},
  year={2010},
  volume={33},
  pages={107-118}
}
White adipose tissue is a promising source of mesenchymal stem cells. Currently, little is known about the effect of age and caloric restriction (CR) on adipose-derived stem cells (ASC). This is important for three reasons: firstly, age and CR cause extensive remodeling of WAT; it is currently unknown how this remodeling affects the resident stem cell population. Secondly, stem cell senescence has been theorized as one of the causes of aging and could reduce the utility of a stem cell as a… CONTINUE READING

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