Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage.

@article{Colom2007CaloricRA,
  title={Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage.},
  author={Bartomeu Colom and Jordi Oliver and Pilar Roca and Francisco Jos{\'e} Garc{\'i}a-Palmer},
  journal={Cardiovascular research},
  year={2007},
  volume={74 3},
  pages={456-65}
}
OBJECTIVE Gender and diet have an important effect in cardiovascular disease and other aging-associated disorders, whose initiation and/or worsening seem to be delayed in females from different species and in animals subjected to caloric restriction (CR). The aim of the present study was to investigate whether cardiac muscle bioenergetic mitochondrial features could be responsible for these beneficial effects. METHODS Fifteen-month-old male and female Wistar rats were fed ad libitum or… CONTINUE READING
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Subfractionation of mitochondria and isolation of the proteins of oxidative phosphorylation

  • CI Ragan, MT Wilson, VM Darley-Usmar, PN. Lowe
  • 1987
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