Caloric restriction ameliorates acrolein-induced neurotoxicity in rats.

Abstract

OBJECTIVE Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant and oxidative damage induced by acrolein is hypothesized to involve in the etiology of Alzheimer's disease (AD). Calorie restriction (CR) is the only non-genetic intervention that has consistently been verified to retard aging by ameliorating oxidative stress… (More)
DOI: 10.1016/j.neuro.2018.01.003

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