Calmodulin-dependent kinase 1beta is expressed in the epiphyseal growth plate and regulates proliferation of mouse calvarial osteoblasts in vitro.

@article{Pedersen2008CalmodulindependentK1,
  title={Calmodulin-dependent kinase 1beta is expressed in the epiphyseal growth plate and regulates proliferation of mouse calvarial osteoblasts in vitro.},
  author={Mona Elisabeth Pedersen and Dario Fortunati and Marit Nyholm Nielsen and Sverre-Henning A Brorson and Tove Lekva and Lise Sofie Haug Nissen-Meyer and Vigdis T. Gautvik and Aboulghassem Shahdadfar and Kaare M. Gautvik and Rune Jemtland},
  journal={Bone},
  year={2008},
  volume={43 4},
  pages={700-7}
}
The Ca(2+)/Calmodulin-dependent protein kinase (CaMK) family is activated in response to elevation of intracellular Ca(2+), and includes CaMK1 (as well as CaMK2 and CaMK4), which exists as different isoforms (alpha, beta, gamma and delta). CaMK1 is present in several cell types and may be involved in various cellular processes, but its role in bone is… CONTINUE READING