Calmodulin activation is required for the enhancement of hippocampal neurogenesis following environmental enrichment

@article{Zhong2009CalmodulinAI,
  title={Calmodulin activation is required for the enhancement of hippocampal neurogenesis following environmental enrichment},
  author={Le Zhong and Chong-huai Yan and Cheng-qiu Lu and Jian Xu and Hua Huang and Xiao-ming Shen},
  journal={Neurological Research},
  year={2009},
  volume={31},
  pages={707 - 713}
}
Abstract Objective: An enriched environmental exposure has been shown to promote hippocampal neurogenesis, which is an important mechanism underlying enrichment-induced memory improvement. The cAMP response element-binding protein is an important stimulus-inducible factor in the brain and is crucial for neurogenesis and memory ability. Calmodulin activation is important for activity-induced cAMP response element-binding protein phosphorylation. The aim of this study was to explore the effects… 
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